Causal Discovery from Biomedical Data – June 8-11, 2015, Carnegie Mellon University, Pittsburgh, PA
Location: Baker Hall, Giant Eagle Auditorium, A51, CMU
Course Director: Richard Scheines, PhD
June 8June 9June 10June 11
Causal Graphical Models – Richard Scheines with Joe Ramsey
- Introduction
- Overview of causal graphical models
- Loading Tetrad
- Causal graphs/interventions
- Building Models
- Parametric models: Bayes nets, Structural Equation Models (SEM), etc.
- Instantiated models
- Estimation
- Estimation
- Inference
- Updating
- Hands-on Real-Data Examples
Dinner on your own, though CCD personnel will be on hand to give advice and rides.
Search – Richard Scheines with Joe Ramsey
- D-Separation
- Model Equivalence
- Search Basics
- PC
- GES
- GES-IDA
- GES Speed-up
- Hands-on Real-Data Examples
- Latent Variable Model Search
- FCI
- SEM search
Break early for Poster Session and Dinner (6-8 pm)
Biomedical Causal Discovery Overview
- Overview of biomedical problems as case studies
- fMRI (brain functional connectome) – Clark Glymour & Ruben Sanchez-Romero
- Cancer genomic drivers – Xinghua Lu
- Lung disease pathways (susceptibility & progression) – Takis Benos
- Genetic regulatory network examples – Peter Spirtes
- Using Background Knowledge
- Time Series
- Handling Feedback
- Unit of Analysis (single unit, neurons, etc.)
Dinner on your own, though CCD personnel will be on hand to give advice and rides.
Biomedical Causal Discovery Case Studies
Attendees choose the biomedical case studies of most interest to them
- Morning case studies
- fMRI (brain functional connectome) – Clark Glymour & Ruben Sanchez-Romero
- Cancer genomic drivers – Xinghua Lu
- Lung disease pathways (susceptibility & progression) – Takis Benos
- Genetic regulatory network examples – Peter Spirtes
- Group Discussion
- Overview by CCD Systems Architecture & Algorithm groups
- Question & answer period
- Interactive discussion of course material
- Attendees discuss the types of datasets they need to model – help guide CCD algorithm development
- CCD user outreach activities