Enabling Precision Genomics at an Enterprise Level

You are invited to a special seminar on Friday, October 23, by Peter S. White, PhD, Rieveschl Professor of Pediatrics, director, Division of Biomedical Informatics, Cincinnati Children’s Hospital Medical Center; professor and chair, Department of Biomedical Informatics, University of Cincinnati College. The seminar, “Enabling Precision Genomics at an Enterprise Level,” will be at 11 a.m. in Conference Room 407 A/B, Fourth Floor, Department of Biomedical Informatics, 5607 Baum Blvd., Pittsburgh, PA 15206.

 Abstract: Genome-based medicine holds substantial promise for moving beyond the treatment of typical patients to the development and application of evidence-based personalized care. Success will depend upon the broadest possible use of phenotypic and molecular data of increasing volume and variety for accelerating disease discovery, translational science, and individualized care to patients. The evolution that is required to ensure a sound future for genome-centered care encompasses technical, data, behavioral, and organizational practices across a diverse set of stakeholders. Enterprise-level commitment is needed to ensure that caregivers, researchers, patients and families, and patient support systems are sufficiently literate and invested in the promise of genomic medicine. The Center for Pediatric Genomics at Cincinnati Children’s Hospital Medical Center is an example of an encompassing model that seeks to define and implement a community of genomics practice across an institution. This presentation will discuss the importance of developing organizational, data, analytical, and technology structures that combine and maximize awareness, learning, and participation for genomic medicine. The Center also integrates with ongoing network research efforts that include healthcare learning systems and multi-institutional collaborations, including the Genomic Research and Innovation Network. Institutional commitments to integrated genomics practice will ensure the progression of genome-based pediatric practice, as well as deeper insights into the molecular basis of complex disorders.